1010833-16-5Relevant articles and documents
Synthesis of 1,3-thiazine-2,4-diones with potential anticancer activity
Ferreira, Misael,Assun??o, Laura Sartori,Filippin-Monteiro, Fabíola Branco,Creczynski-Pasa, Tania Beatriz,Sá, Marcus Mandolesi
, p. 411 - 418 (2013/11/19)
2-Amino-1,3-thiazin-4-ones were subjected to acetylation followed by mild acid hydrolysis to give compounds containing the 1,3-thiazine-2,4-dione core. The potential of these S,N-containing heterocycles as antitumor agents against human cancer cell lines,
Synthesis of allylic thiocyanates and novel 1,3-thiazin-4-ones from 2-(bromomethyl)alkenoates and S-nucleophiles in aqueous medium
Sá, Marcus M.,Fernandes, Luciano,Ferreira, Misael,Bortoluzzi, Adailton J.
, p. 1228 - 1232 (2008/09/17)
Allylic thiocyanates and novel heterocycles containing the 1,3-thiazin-4-one core are easily obtained in high yields and mild conditions by nucleophilic displacement of 2-(bromomethyl)alkenoates (derived from Morita-Baylis-Hillman adducts) with sulphur-ce