101096-72-4

Usage

Uses

Used in Pharmaceutical Industry:
4-BENZYLPHENYLACETONITRILE is used as a key intermediate in the synthesis of various drugs and pharmaceutical products for its ability to contribute to the development of medications with diverse therapeutic properties.
Used in Anti-inflammatory Medications:
4-BENZYLPHENYLACETONITRILE is used as a chemical component in the production of anti-inflammatory drugs, aiding in the management of conditions characterized by inflammation and pain.
Used in Antifungal Medications:
4-BENZYLPHENYLACETONITRILE is utilized as a constituent in antifungal medications, playing a role in combating fungal infections and promoting overall health.
Used in Antibacterial Medications:
4-BENZYLPHENYLACETONITRILE is employed as a component in antibacterial formulations, contributing to the fight against bacterial infections and supporting treatment outcomes.
Used in Fragrance and Flavoring Industry:
4-BENZYLPHENYLACETONITRILE is used as a raw material in the manufacturing of fragrances and flavorings, capitalizing on its chemical properties to create a variety of scents and tastes for consumer products.

InChI:InChI=1/C15H13N/c16-11-10-13-6-8-15(9-7-13)12-14-4-2-1-3-5-14/h1-9H,10,12H2

Upstream product

• 54588-96-4 1-(bromomethyl)-4-(phenylmethyl)-benzene 
• 143-33-9 sodium cyanide 
• 69410-45-3 3-benzyl-1-bromomethylbenzene 
• 14297-39-3 4-benzylbenzyl chloride 
• 773837-37-9 sodium cyanide 
• 98-80-6 phenylboronic acid 

Downstream Products

• 18908-75-3 (4-benzyl-phenyl)-acetic acid ethyl ester 
• 208042-64-2 4-benzylphenylacetamide 
• 18908-81-1 [4-(4-{4-[4-(4-Ethoxycarbonylmethyl-benzyl)-benzoyl]-benzoyl}-benzyl)-phenyl]-acetic acid ethyl ester 
• 18908-91-3 [4-(4-{4-[4-(4-Ethoxycarbonylmethyl-benzyl)-benzyl]-benzyl}-benzyl)-phenyl]-acetic acid ethyl ester 
• 101733-51-1 2-(4-benzyl-phenyl)-pent-4-enenitrile 
• 101282-97-7 2-(4-benzyl-phenyl)-propionitrile 
• 35889-03-3 2-(4-benzylphenyl)acetic acid 
• 101876-91-9 2-(4-benzyl-phenyl)-butyronitrile 

Relevant academic research and scientific papers

Substrate switchable Suzuki-Miyaura coupling for benzyl ester: Vs. benzyl halide

Two reaction conditions were developed to accomplish the substrate switchable Suzuki-Miyaura coupling of benzyl derivatives and arylboronic acid derivatives. Under conditions for esters, benzyl esters such as carbonates and acetates reacted with arylboronic acids to afford the corresponding diarylmethanes. However, the benzyl halides did not react under the same conditions. On the other hand, benzyl halides such as bromides and chlorides furnished diarylmethanes under conditions for halides, under which benzyl ester substrates did not react, in which water was found to play an important role. This switching system was tested using the intermolecular/intramolecular competitive reactions, during which the desired products could be synthesized by selecting the appropriate reaction conditions.

Phenyl acetamides as sPLA2 inhibitors

A class of novel phenyl acetamides is disclosed together with the use of such compounds for inhibiting sPLA2mediated release of fatty acids for treatment of conditions such as septic shock.

CONDENSED PYRAZOLE DERIVATIVES, METHOD OF MANUFACTURING THE SAME, AND ANDROGEN INHIBITOR

This invention provides a condensed pyrazole derivative of the Formula (1): STR1 (where A denotes CH or N, R 0 and R 3 denote same or different, a hydrogen atom or a lower alkyl group, R 1 and R 2 denote same or different, a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a nitro group or a halogen atom, m denotes 1 or 2, and n denotes 1, 2 or 3, provided that, when n is 2, two R 2 may be connected to each other to form a lower alkylenedioxy group), or its pharmaceutically acceptable salt. This derivative or its salt is excellent in the effect of inhibiting the expression of action of androgen, thereby being excellent in therapeutical effect of benign prostatic hypertrophy, prostatic carcinoma, etc., and has a long lasting of efficacy and high oral absorption.