1011247-68-9

Basic information

• Product Name: (4R,5S,Z)-4-(benzyloxy)-5-((tert-butoxycarbonyl)amino)-6-hydroxyhex-2-en-1-yl acetate
• Synonyms: (4R,5S,Z)-4-(benzyloxy)-5-((tert-butoxycarbonyl)amino)-6-hydroxyhex-2-en-1-yl acetate
• CAS NO: 1011247-68-9
• Molecular Weight: 379.453
• Mol File: 1011247-68-9.mol

Chemical Properties

• CAS DataBase Reference: (4R,5S,Z)-4-(benzyloxy)-5-((tert-butoxycarbonyl)amino)-6-hydroxyhex-2-en-1-yl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5S,Z)-4-(benzyloxy)-5-((tert-butoxycarbonyl)amino)-6-hydroxyhex-2-en-1-yl acetate(1011247-68-9)
• EPA Substance Registry System: (4R,5S,Z)-4-(benzyloxy)-5-((tert-butoxycarbonyl)amino)-6-hydroxyhex-2-en-1-yl acetate(1011247-68-9)

Safety Data

• Hazardous Substances Data: 1011247-68-9(Hazardous Substances Data)

Upstream product

• 1011247-62-3 (S)-tert-butyl 4-((R,Z)-1-(benzyloxy)-4-((tert-butyldimethylsilyl)oxy)but-2-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 
• 1011247-64-5 (S)-tert-butyl 4-((R,Z)-1-(benzyloxy)-4-hydroxybut-2-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 
• 1011247-66-7 (S)-tert-butyl 4-((R,Z)-4-acetoxy-1-(benzyloxy)but-2-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 

Downstream Products

• 1011247-72-5 tert-butyl ((3S,4S,5S)-4-(benzyloxy)-5-vinyltetrahydrofuran-3-yl)carbamate 
• 1011247-70-3 tert-butyl ((3S,4S,5R)-4-(benzyloxy)-5-vinyltetrahydrofuran-3-yl)carbamate 
• 1011247-74-7 tert-butyl ((3S,4S,5S)-4-(benzyloxy)-5-((E)-tetradec-1-en-1-yl)tetrahydrofuran-3-yl)carbamate 
• 1287228-25-4 tert-butyl ((3S,4S,5R)-4-(benzyloxy)-5-((E)-tetradec-1-en-1-yl)tetrahydrofuran-3-yl)carbamate 

Relevant articles and documents

Asymmetric synthesis of Pachastrissamine (Jaspine B) and its diastereomers via η3-allylpalladium intermediates

A short route for the synthesis of Pachastrissamine (Jaspine B), an anhydrosphingosine derivative, and all three of its diastereomers is presented. The route consists of only 9 steps from the commercially available Garner's aldehyde. The furan framework is formed via an η3-allylpalladium intermediate.

Stereoselective total synthesis of pachastrissamine (jaspine B)

A short total synthesis of the cytotoxic natural product pachastrissamine is described. The synthesis includes eight steps starting from Garner's aldehyde and proceeds in 20% overall yield. Pd(0)-mediated intramolecular cyclisation and Ru-mediated cross-metathesis are the key reactions in this sequence.