1011247-72-5Relevant articles and documents
Asymmetric synthesis of Pachastrissamine (Jaspine B) and its diastereomers via η3-allylpalladium intermediates
Passiniemi, Mikko,Koskinen, Ari M. P.
experimental part, p. 1774 - 1783 (2011/05/04)
A short route for the synthesis of Pachastrissamine (Jaspine B), an anhydrosphingosine derivative, and all three of its diastereomers is presented. The route consists of only 9 steps from the commercially available Garner's aldehyde. The furan framework is formed via an η3-allylpalladium intermediate.
Stereoselective total synthesis of pachastrissamine (jaspine B)
Passiniemi, Mikko,Koskinen, Ari M.P.
, p. 980 - 983 (2008/09/17)
A short total synthesis of the cytotoxic natural product pachastrissamine is described. The synthesis includes eight steps starting from Garner's aldehyde and proceeds in 20% overall yield. Pd(0)-mediated intramolecular cyclisation and Ru-mediated cross-metathesis are the key reactions in this sequence.