1011716-97-4

Basic information

• Product Name: Benzoic acid, 4-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-6-yl)-, Methyl ester
• Synonyms: Benzoic acid, 4-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-6-yl)-, Methyl ester;Methyl 4-(4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoate
• CAS NO: 1011716-97-4
• Molecular Formula: C₁₄H₁₁N₃O₃
• Molecular Weight: 269.25544
• Mol File: 1011716-97-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 560.5±60.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 15.50±0.20(Predicted)
• CAS DataBase Reference: Benzoic acid, 4-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-6-yl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-6-yl)-, Methyl ester(1011716-97-4)
• EPA Substance Registry System: Benzoic acid, 4-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-6-yl)-, Methyl ester(1011716-97-4)

Safety Data

• Hazardous Substances Data: 1011716-97-4(Hazardous Substances Data)

Upstream product

• 3609-53-8 methyl 4-acetylbenzoate 
• 64-18-6 formic acid 
• 1011716-95-2 ethyl 2-amino-5-(4-(methoxycarbonyl)phenyl)-1H-pyrrole-3-carboxylate 
• 77287-34-4 formamide 
• 56893-25-5 methyl 4-(2-bromoacetyl)benzoate 

Downstream Products

• 1011717-00-2 methyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoate 
• 863307-00-0 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoic acid 
• 863307-01-1 [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone 

Relevant articles and documents

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF

The present disclosure relates to a class of substituted bicyclic compounds of formula (I), their tautomers, polymorphs, stereoisomers, prodrugs, solvates, hydrates, N-oxides, co-crystals, pharmaceutically acceptable salts and pharmaceutical compositions

MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS

The present invention relates to the compositions, methods, and applications of a novel approach to selective inhibition of several cellular or molecular targets with a single small molecule. More specifically, the present invention relates to multi-functional small molecules wherein one functionality is capable of inhibiting histone deacetylases (HDAC) and the other functionality is capable of inhibiting a different cellular or molecular pathway involved in aberrant cell proliferation, differentiation or survival.