1012057-49-6

Basic information

• Product Name: methyl 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylcarbamoyl)butanoate
• Synonyms: methyl 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylcarbamoyl)butanoate
• CAS NO: 1012057-49-6
• Molecular Weight: 446.866
• Mol File: 1012057-49-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylcarbamoyl)butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylcarbamoyl)butanoate(1012057-49-6)
• EPA Substance Registry System: methyl 3-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ylcarbamoyl)butanoate(1012057-49-6)

Safety Data

• Hazardous Substances Data: 1012057-49-6(Hazardous Substances Data)

Upstream product

• 179552-75-1 N⁴-(3-chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 

Downstream Products

• 1012054-73-7 N₁-(4-(3-chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl)-N₅-hydroxyglutaramide 

Relevant articles and documents

MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS

The present invention relates to the compositions, methods, and applications of a novel approach to selective inhibition of several cellular or molecular targets with a single small molecule. More specifically, the present invention relates to multi-functional small molecules wherein one functionality is capable of inhibiting histone deacetylases (HDAC) and the other functionality is capable of inhibiting a different cellular or molecular pathway involved in aberrant cell proliferation, differentiation or survival.