101207-50-5Relevant articles and documents
Highly enantioselective enzymatic resolution of aromatic β-amino acid amides with Pd-catalyzed racemization
Kim, Mahn-Joo,Choi, Eunjeong,Kim, Yunwoong,Ahn, Yangsoo,Park, Jaiwook
, p. 1449 - 1452 (2013/12/04)
The kinetic resolution of an aromatic β-amino acid amide 3a-d via N-acylation was explored with two lipases, Candida antarctica lipase A (CALA) and Pseudomonas stutzeri lipase (PSL). The PSL-catalyzed resolution proceeded with excellent enantioselectivity
Amidine derivatives and cardiotonic compositions
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, (2008/06/13)
Amidine derivatives of the formula STR1 wherein R1 and R2, which may be the same or different, represent each a hydrogen atom or a lower alkyl group, or R1 and R2 together with an intermediary carbon atom and/or hetero atom may form a ring; X represents STR2 (wherein R8 represents a hydrogen atom, a lower alkyl group, or --CH2 COOR9, where R9 represents a hydrogen atom or a lower alkyl group; Z represents a single bond, --CH2 --, --CH2 CH2 --, or --CH=CH--); R3 represents a hydrogen or chlorine atom, methoxy group, nitro group, or amino group; Y represents --CH2 CH2 --, --CH=CH--, --CH2 O--, or --OCH2 --; R4 represents a hydrogen atom, methoxy group, benzoyl group, nitro group, or amino group; and R5, R6 and R7, which may be the same or different, represent each a hydrogen atom, lower alkyl group, cycloalkyl group, aralkyl group, substituted alkyl group, substituted aralkyl group, or amino group, or R5 and R7 may form a ring, or salts thereof have an excellent cardiotonic activity and can be used as cardiotonics.