101231-95-2Relevant academic research and scientific papers
Enantioselective Cyclopropanation/[1,5]-Hydrogen Shift to Access Rauhut-Currier Product
Kim, Seung Tae,Pandit, Rameshwar Prasad,Yun, Jaesook,Ryu, Do Hyun
supporting information, p. 213 - 217 (2021/01/09)
A Michael addition initiated cyclopropanation/[1,5]-hydrogen shift has been developed for the enantioselective synthesis of Rauhut-Currier products. The reaction of α-alkyl diazoesters and in situ generated o-quinone methides proceeds in the presence of c
A Simple Synthesis of Densely Substituted Benzofurans by Domino Reaction of 2-Hydroxybenzyl Alcohols with 2-Substituted Furans
Abaev, Vladimir T.,Chalikidi, Petrakis N.,Kekhvaeva, Anna E.,Makarov, Anton S.,Trushkov, Igor V.,Uchuskin, Maxim G.
, p. 3747 - 3757 (2019/09/30)
The Br?nsted acid-catalyzed cascade synthesis of densely substituted benzofurans from easily available salicyl alcohols and biomass-derived furans has been developed. The disclosed sequence includes the intermediate formation of 2-(2-hydroxybenzyl)furans
Multicomponent Condensation Reactions via ortho-Quinone Methides
Allen, Emily E.,Zhu, Calvin,Panek, James S.,Schaus, Scott E.
, p. 1878 - 1881 (2017/04/11)
Iron(III) salts promote the condensation of aldehydes or acetals with electron-rich phenols to generate ortho-quinone methides that undergo Diels - Alder condensations with alkenes. The reaction sequence occurs in a single vessel to afford benzopyrans in up to 95% yield. The reaction was discovered while investigating a two-component strategy using 2-(hydroxy(phenyl)methyl)phenols to access the desired ortho-quinone methide in a Diels - Alder condensation. The two-component condensation also afforded the corresponding benzopyran products in yields up to 97%. Taken together, the two- and three-component strategies using ortho-quinone methide intermediates provide efficient access to benzopyrans in good yields and selectivities.
A monolith immobilised iridium Cp catalyst for hydrogen transfer reactions under flow conditions
Rojo, Maria Victoria,Guetzoyan, Lucie,Baxendale, Ian. R.
, p. 1768 - 1777 (2015/02/19)
An immobilised iridium hydrogen transfer catalyst has been developed for use in flow based processing by incorporation of a ligand into a porous polymeric monolithic flow reactor. The monolithic construct has been used for several redox reductions demonstrating excellent recyclability, good turnover numbers and high chemical stability giving negligible metal leaching over extended periods of use.
Palladium catalyzed isomerization of alkenes: A pronounced influence of an o-phenol hydroxyl group
Fan, Jinmin,Wan, Changfeng,Wang, Qiang,Gao, Linfeng,Zheng, Xiaoqi,Wang, Zhiyong
supporting information; experimental part, p. 3168 - 3172 (2011/02/25)
A novel palladium catalyzed isomerization of alkenes has been found, where an ortho-phenol hydroxyl group has a pronounced influence on the isomerization.
Facile construction of functionalized 4H-chromene via tandem benzylation and cyclization
Fan, Jinmin,Wang, Zhiyong
supporting information; experimental part, p. 5381 - 5383 (2009/03/11)
A series of functionalized 4H-chromenes have been constructed by using a novel FeCl3-catalyzed benzylation-cyclization tandem reaction. The Royal Society of Chemistry.
A Convenient Route to ortho-Alkylated Phenols and Quinone Monoacetals
Chen, Chung-Pin,Swenton, John S.
, p. 1291 - 1292 (2007/10/02)
An efficient, regiospecific, convergent route to o-alkylated phenols and thence to quinone monoacetals involves reaction of the corresponding 2-hydroxy carbonyl derivative with alkyl-lithium reagents, followed by triethylsilane reduction and electrochemic
