1012367-19-9

Basic information

• Product Name: (E)-methyl (3-phenylallyl)(tosyl)carbamate
• Synonyms: (E)-methyl (3-phenylallyl)(tosyl)carbamate
• CAS NO: 1012367-19-9
• Molecular Weight: 345.419
• Mol File: 1012367-19-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (E)-methyl (3-phenylallyl)(tosyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl (3-phenylallyl)(tosyl)carbamate(1012367-19-9)
• EPA Substance Registry System: (E)-methyl (3-phenylallyl)(tosyl)carbamate(1012367-19-9)

Safety Data

• Hazardous Substances Data: 1012367-19-9(Hazardous Substances Data)

Upstream product

• 300-57-2 allylbenzene 
• 14437-03-7 methyl tosylcarbamate 

Relevant articles and documents

A Bulky Disulfoxide Ligand for Pd-Catalyzed Oxidative Allylic C-H Amination with 2,2,2-Trichloroethyl Tosyl Carbamate

Challenging substrates and conditions in homogeneous catalysis pose stringent demands on the ligands used. A novel, bulky, 1-adamantyl-substituted disulfoxide ligand designed after a systematic evaluation of the electronic and steric properties of disulfoxide substituents permits the allylic oxidative C-N coupling reaction to proceed at lower catalyst loading while requiring a smaller excess of reagents. Additionally, this ligand improves the yields when TsNHCOOCH2CCl3, a novel reagent that permits deprotection of the products under both acidic and basic conditions, is used.

Palladium-catalyzed allylic C-H amination of alkenes with N-fluorodibenzenesulfonimide: Water plays an important role

A new palladium-catalyzed highly regioselective allylic C-H amination of alkenes with NFSI in the presence of a catalytic amount of water was developed and successfully expanded to Selectfluor-mediated palladium-catalyzed aminations of alkenes with N-tosy

Palladium-catalyzed intermolecular aerobic oxidative amination of terminal alkenes: Efficient synthesis of linear allylamine derivatives

(Chemical Equation Presented) O2-coupledallylic C-H amination: A first general palladium-mediated intermolecular aerobic oxidative allylic amination was developed to synthesize linear (E)-allylimides with high regioselectivity (see scheme; MA = maleic anhydride). The proposed mechanism involves an allylic C-H activation with subsequent nitrogen nucleophile substitution. The catalytic system allows efficient dioxygen-coupled turnover without additional cocatalysts.