1012367-23-5

Basic information

• Product Name: C₃₁H₃₂N₂O₈S
• Synonyms: C₃₁H₃₂N₂O₈S
• CAS NO: 1012367-23-5
• Molecular Weight: 592.67
• Mol File: 1012367-23-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₁H₃₂N₂O₈S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₁H₃₂N₂O₈S(1012367-23-5)
• EPA Substance Registry System: C₃₁H₃₂N₂O₈S(1012367-23-5)

Safety Data

• Hazardous Substances Data: 1012367-23-5(Hazardous Substances Data)

Upstream product

• 1012367-40-6 (S)-2-(1-((4-methoxybenzyl)oxy)hex-5-en-2-yl)isoindoline-1,3-dione 
• 14437-03-7 methyl tosylcarbamate 

Relevant articles and documents

Catalytic intermolecular linear allylic C-H amination via heterobimetallic catalysis

A novel heterobimetallic Pd(II)sulfoxide/(salen)Cr(III)Cl-catalyzed intermolecular linear allylic C-H amination (LAA) is reported. This reaction directly converts densely functionalized α-olefin substrates (1 equiv) to linear (E)-allylic carbamates with good yields and outstanding regio- and stereoselectivities (>20:1). Chiral bis-homoallylic and homoallylic oxygen, nitrogen, and carbon substituted α-olefins undergo allylic C-H amination with good yields, excellent selectivities, and no erosion in enantiomeric purity. Streamlined routes to (E)-allylic carbamates that can be further elaborated to medicinally and biologically relevant allylic amines are also demonstrated. Valuable 15N-labeled allylic amines may be generated directly from allyl moieties at late stages of synthetic routes by using the readily available 15N-(methoxycarbonyl)-p-toluenesulfonamide nucleophile. Evidence is provided that this reaction proceeds via a heterobimetallic mechanism where Pd/sulfoxide mediates allylic C-H cleavage to form a π-allylPd intermediate, and (salen)Cr(III)Cl/BQ work together to promote functionalization with the nitrogen nucleophile. Copyright