101248-37-7Relevant articles and documents
Folate Analogues. 26. Syntheses of Antifolate Activity of 10-Substituted Derivatives of 5,8-Dideazafolic Acid and of the Poly-γ-glutamyl Metabolites of N10-Propargyl-5,8-Dideazafolic Acid (PDDF)
Nair, M.G.,Nanavati, Nitin T.,Nair, Indira G.,Kisliuk, Roy L.,Gaumont, Y.,et al.
, p. 1754 - 1760 (2007/10/02)
The poly-γ-glutamyl derivatives of N10-propargyl-5,8-dideazafolic acid (PDDF) with a chain length of up to five glutamate residues were synthesized from N10-propargyl-5,8-dideazapteroic acid (7) by the solid-phase procedure.These com