101248-32-2

Basic information

• Product Name: 4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoic acid
• CAS NO: 101248-32-2
• Molecular Formula: C₁₉H₁₆N₄O₃
• Molecular Weight: 348.3553
• Mol File: 101248-32-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 652°C at 760 mmHg
• Flash Point: 348.1°C
• Density: 1.33g/cm³
• Vapor Pressure: 6.88E-18mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: 4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoic acid(101248-32-2)
• EPA Substance Registry System: 4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoic acid(101248-32-2)

Safety Data

• Hazardous Substances Data: 101248-32-2(Hazardous Substances Data)

Upstream product

• 619-45-4 4-methoxycarbonyl aniline 
• 58677-07-9 N-[6-(bromomethyl)-3,4-dihydro-4-oxo-2-quinazolinyl]-2,2-dimethylpropanamide 
• 50440-82-9 2-amino-3,4-dihydro-6-methyl-4-oxoquinazoline 
• 101248-37-7 ethyl 4-prop-2-ynylamino>benzoate 
• 77766-62-2 2-amino-6-(bromomethyl)-4-hydroxyquinazoline hydrobromide 
• 101248-36-6 ethyl 4-(prop-2-ynylamino)benzoate 

Relevant articles and documents

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Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.

Quinazoline antifolates inhibiting thymidylate synthase: Variation of the amino acid

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