1013-24-7

Basic information

• Product Name: 1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE
• Synonyms: 1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE;Methylmercaptophenylpiperazine;1-[2-(Methylthio)phenyl]piperazine;1-[2-(Methylthio)phenyl]piperazine 96%;1-[2-(Methylsulfanyl)phenyl]piperazine;1-[2-(Methylthio)phenyl]piperazine96%
• CAS NO: 1013-24-7
• Molecular Formula: C₁₁H₁₆N₂S
• Molecular Weight: 208.32
• Mol File: 1013-24-7.mol

Chemical Properties

• Boiling Point: 139 °C
• Flash Point: 160.7 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 7.67E-05mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE(1013-24-7)
• EPA Substance Registry System: 1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE(1013-24-7)

Safety Data

• Hazard Codes: Xi,T
• Statements: 36/37/38-25
• Safety Statements: 26-36/37/39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 1013-24-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-METHYLMERCAPTOPHENYL)PIPERAZINE is used as a pharmaceutical intermediate for the development of various medications due to its biological activity as a serotonin receptor antagonist. Its role in this capacity aids in the treatment of a range of conditions that may involve serotonin dysregulation.

InChI:InChI=1/C11H16N2S/c1-14-11-5-3-2-4-10(11)13-8-6-12-7-9-13/h2-5,12H,6-9H2,1H3

Upstream product

• 2987-53-3 2-(Methylthio)aniline 
• 43204-63-3 bis(2-bromoethyl)amine hydrobromide 

Downstream Products

• 313490-26-5 1-[2-(methylsulfonyl)phenyl]piperazine 
• 1052401-82-7 2-[6-[4-(2-methylthiophenyl)-1-piperazinyl]-1-oxohexyl]isoindoline 
• 1052401-83-8 2-[6-[4-(2-methylthiophenyl)-1-piperazinyl]-1-oxohexyl]-1,2,3,4-tetrahydroisoquinoline 
• 1052147-76-8 4-(2-methylthiophenyl)-N-(4-pyridinylmethyl)-1-piperazinehexanamide 
• 1052401-92-9 N-(4-cyanophenylmethyl)-4-(2-methylthiophenyl)-1-piperazinehexanamide 
• 1052401-94-1 N-(4-methanesulfonyloxyphenylmethyl)-4-(2-methylthiophenyl)-1-piperazinehexanamide 
• 1052401-86-1 N-benzyl-4-(2-methylthiophenyl)-1-piperazinehexanamide 
• 1178860-83-7 3-[4-(2-methylsulfanylphenyl)piperazin-1-yl]propionitrile 
• 291510-91-3 1-[(2-Ethoxyquinoxalin-3-yl)aminocarbonyl]-4-(2-methylthiophenyl)-piperazine 
• 291510-24-2 1-[(5,6-Dimethyl-2-methoxypyrazin-3-yl)aminocarbonyl]-4-(2-methylthiophenyl)piperazine 
• 534606-53-6 4-[2,5-Dihydro-3-methyl-4-[5-[4-[2-(methylsulfanyl)phenyl]piperazin-1-yl]pentyl]-2,5-dioxo-1H-pyrrol-1-yl]-2-(trifluoromethyl)benzonitrile 

Relevant articles and documents

Trifluoromethylquinolinecarboxylic acid derivative

This invention relates to a 8-trifluoromethylquinolinecaboxylic acid derivative represented by the following formula (I): (wherein R1 represents a lower alkyl group, a halogeno-lower alkyl group or a cycloalkyl group, R2 represents a phenyl group which may be substituted by R0, a 5-membered or 6-membered aromatic heteromonocyclic ring group containing 1 or 2 hetero atoms selected from N, O and S, which may be substituted by R0, or an aromatic heterocyclic fused ring group in which the said aromatic heteromonocyclic ring group and a benzene ring are fused, R0 represents a group selected from a halogen, a lower alkyl, a fluorine-substituted lower alkyl, a lower alkoxy or a lower alkylthio, R3 represents hydrogen or a lower alkyl group, and m represents an integer of 2 or 3.) or a pharmaceutically acceptable salt thereof or an ester thereof.

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