10130-25-3

Basic information

• Product Name: 2-ethyl-3-phenylquinoxaline
• Synonyms: 2-ethyl-3-phenylquinoxaline
• CAS NO: 10130-25-3
• Molecular Weight: 234.301
• Mol File: 10130-25-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-ethyl-3-phenylquinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethyl-3-phenylquinoxaline(10130-25-3)
• EPA Substance Registry System: 2-ethyl-3-phenylquinoxaline(10130-25-3)

Safety Data

• Hazardous Substances Data: 10130-25-3(Hazardous Substances Data)

Upstream product

• 622-76-4 1-phenyl-1-butyne 
• 95-54-5 1,2-diamino-benzene 
• 495-40-9 propiophenone 
• 3457-55-4 1-phenyl-1,2-butanedione 

Downstream Products

• 1400975-26-9 1,3-dimethyl-4-phenylpyrrolo[1,2-a]quinoxaline 
• 1415584-23-4 2-phenyl-3-(prop-1-en-2-yl)quinoxaline 

Relevant articles and documents

A highly cis-selective and enantioselective metal-free hydrogenation of 2,3-disubstituted quinoxalines

A wide range of 2,3-disubstituted quinoxalines have been successfully hydrogenated with H2 using borane catalysts to produce the desired tetrahydroquinoxalines in 80-99% yields with excellent cis selectivity. Significantly, the asymmetric reaction employing chiral borane catalysts generated by the in situ hydroboration of chiral dienes with HB(C6F5)2 under mild reaction conditions has also been achieved with up to 96% ee, and represents the first catalytic asymmetric system to furnish optically active cis-2,3-disubstituted 1,2,3,4-tetrahydroquinoxalines.

Synthesis of α-heterosubstituted ketones through sulfur mediated difunctionalization of internal alkynes

Synthesis of α-heterosubstituted ketones was achieved through sulfur mediated difunctionalization of internal alkynes in one pot. The reaction design involves: phenyl substituted internal alkyne attacking triflic anhydride activated diphenyl sulfoxide to

Elemental iodine or diphenyl diselenide in the [bis(trifluoroacetoxy)iodo] benzene-mediated conversion of alkynes into 1,2-diketones

Both elemental iodine and diphenyl diselenides, in the presence of [bis(trifluoroacetoxy)iodo]benzene (PIFA), promote the transformation of internal alkynes into the corresponding 1,2-diketones. The reactions carried out in the presence of iodine unfortunately did not proceed with complete conversion of the starting alkynes. On the other hand, diphenyl diselenide was more efficient and gave satisfactory transformation of the starting alkynes into 1,2-diketones in better yields. The structure of the vicinal dicarbonyl compounds were confirmed by applying a subsequent condensation reaction to construct the corresponding quinoxaline derivatives. Both elemental iodine and diphenyl diselenide in the presence of [bis(trifluoroacetoxy)iodo]benzene (PIFA) promote the transformation of internal alkynes into 1,2-diketones. The structure of the products were confirmed by transformation into the corresponding quinoxaline derivatives, two of which were studied by X-ray analysis. Copyright