3457-55-4

Basic information

• Product Name: 1-phenylbutane-1,2-dione
• CAS NO: 3457-55-4
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.1852
• Mol File: 3457-55-4.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 245.8°C at 760 mmHg
• Flash Point: 92.5°C
• Density: 1.073g/cm³
• Vapor Pressure: 0.0281mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: 1-phenylbutane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenylbutane-1,2-dione(3457-55-4)
• EPA Substance Registry System: 1-phenylbutane-1,2-dione(3457-55-4)

Safety Data

• Hazardous Substances Data: 3457-55-4(Hazardous Substances Data)

Usage

General Description

1-Phenylbutane-1,2-dione, also known as dibenzoylmethane, is a chemical compound with the molecular formula C15H12O2. It is commonly used as a sunscreen ingredient due to its ability to absorb ultraviolet (UV) radiation. In addition to its UV-absorbing properties, 1-phenylbutane-1,2-dione also exhibits potential antioxidant activity, making it a popular ingredient in skincare products. This chemical compound has also been studied for its potential anti-inflammatory properties and is being researched for its potential use in the treatment of various skin conditions. Overall, 1-phenylbutane-1,2-dione is a versatile compound with significant potential applications in the cosmetic and pharmaceutical industries.

Upstream product

• 127311-59-5 α-nitrato n-propyl phenyl ketone 
• 93-89-0 benzoic acid ethyl ester 
• 105-37-3 Ethyl propionate 
• 35812-01-2 N-bromosaccharin 
• 495-40-9 propiophenone 
• 1007-32-5 benzyl ethyl ketone 
• 67-68-5 dimethyl sulfoxide 
• 824-90-8 1-phenylbut-1-ene 
• 7664-93-9 sulfuric acid 
• 873989-37-8 1-phenyl-2,3-dipiperidino-butan-1-one 
• 16183-45-2 1-hydroxy-1-phenylbutan-2-one 
• 17180-62-0 (3-methyloxiran-2-yl)(phenyl)methanone 
• 557-20-0 diethylzinc 
• 50417-71-5 (benzoyl)PdI(triphenylphosphine)2 

Downstream Products

• 71895-99-3 2-ethylamino-1-phenyl-butan-1-ol 
• 92-52-4 biphenyl 
• 100-52-7 benzaldehyde 
• 134-81-6 benzil 
• 65-85-0 benzoic acid 
• 93-58-3 benzoic acid methyl ester 
• 93-97-0 benzoic acid anhydride 
• 98-86-2 acetophenone 
• 130925-78-9 2-Benzyl-2-hydroxy-1-phenyl-butan-1-one 
• 130925-75-6 2-Hydroxy-1,2-diphenyl-pentan-3-one 
• 130925-77-8 2-Ethyl-2-hydroxy-1-phenyl-pent-4-en-1-one 
• 130925-74-5 4-Hydroxy-4-phenyl-hept-6-en-3-one 
• 139386-82-6 4-<1-(5-phenyl-2-thio-4-imidazolinyl)ethyl>-5-phenyl-4-imidazoline-2-thione 
• 139386-71-3 4-ethylene-1,3-dimethyl-5-phenyl-4-imidazoline-2-thione 

Relevant articles and documents

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Catalyst-Free and Transition-Metal-Free Approach to 1,2-Diketones via Aerobic Alkyne Oxidation

A catalyst-free and transition-metal-free method for the synthesis of 1,2-diketones from aerobic alkyne oxidation was reported. The oxidation of various internal alkynes, especially more challenging aryl-alkyl acetylenes, proceeded smoothly with inexpensive, easily handled, and commercially available potassium persulfate and an ambient air balloon, achieving the corresponding 1,2-diketones with up to 85% yields. Meanwhile, mechanistic studies indicated a radical process, and the two oxygen atoms in the 1,2-diketons were most likely from persulfate salts and molecular oxygen, respectively, rather than water.

Visible light-induced aerobic oxidation of diarylalkynes to α-diketones catalyzed by copper-superoxo at room temperature

We have developed the visible light induced simple copper(ii) chloride catalyzed oxidation of diarylacetylenes to α-diketones by molecular oxygen at room temperature. The in situ generated copper(ii)-superoxo complex is a light-absorbing species that oxidizes inert diarylacetylenes to α-diketones. In contrast to reported photochemical processes, the current oxidation protocol does not require any exogenous photocatalyst or radical initiator. The green chemistry metrics evaluation signifies that the E-factor for the current oxidation process is ～2.3 times better than that of reported photochemical processes. The current reaction scores 63 on the EcoScale of 0-100, indicating an adequate synthesis process. Thus, the overall oxidation process is simple, environmentally benign, and economically feasible. This journal is

ICl/AgNO3 Co-catalyzed radical oxidation of diaryl- A nd alkylarylalkynes into 1,2-diketones

A novel ICl/AgNO3 co-catalyzed radical oxidation of diaryl- A nd alkylarylalkynes into 1,2-diketones is reported. The reaction proceeded smoothly under mild conditions and generated 1,2-diketones in moderate to good yields with a good tolerance of functional groups. Furthermore, the obtained C4-(1,2-diketoaryl)isoxazoles could react smoothly with 1,2-diaminobenzene to form C4-(3-arylquinoxalin-2-yl)isoxazoles. At last, a new one-pot strategy for the synthesis of quinoxalines from 1,2-diphenylethynes and 1,2-diaminobenzene is also reported.