1013036-32-2Relevant academic research and scientific papers
Direct C-glycosylation by indium-mediated alkynylation on sugar anomeric position
Lubin-Germain, Nadge,Baltaze, Jean-Pierre,Coste, Alexis,Hallonet, Agns,Laurano, Hugo,Legrave, Grgory,Uziel, Jacques,Aug, Jacques
, p. 725 - 728 (2008)
Indium-mediated alkynylation reaction was studied for the direct preparation of C-glycosides. Easily available starting sugar derivatives with an acetyl group at the anomeric position were tested as electrophiles toward alkynylindium reagents under Barbier conditions. Good yields and stereoselectivities were observed during the reaction. The alkynylation was applied to the synthesis of an α-(1-6)-C-disaccharide analogue of isomaltoside.
