Welcome to LookChem.com Sign In|Join Free

CAS

  • or

1013099-51-8

trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1013099-51-8 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 1013099-51-8 Structure

  • Basic information

    1. Product Name: trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol
    2. Synonyms: trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol
    3. CAS NO:1013099-51-8
    4. Molecular Formula:
    5. Molecular Weight: 379.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1013099-51-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(1013099-51-8)
    11. EPA Substance Registry System: trans-4-{[5-bromo-2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyrimidin-4-yl]amino}cyclohexanol(1013099-51-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1013099-51-8(Hazardous Substances Data)

1013099-51-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1013099-51-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,3,0,9 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1013099-51:
(9*1)+(8*0)+(7*1)+(6*3)+(5*0)+(4*9)+(3*9)+(2*5)+(1*1)=108
108 % 10 = 8
So 1013099-51-8 is a valid CAS Registry Number.

1013099-51-8Relevant articles and documents

Protein Kinase Inhibitors

-

Paragraph 0180; 0181; 0182, (2014/02/16)

The present invention is directed to compounds of the Formula I as well as pharmaceutically acceptable salts, hydrates, isomers, or solvates thereof, wherein the variables are described herein. The present invention further relates to pharmaceutical compositions which comprise the compounds of Formula I, and to methods for inhibiting protein kinase and methods of treating diseases, such as cancers, inflammation.

Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series

Cheng, Hengmiao,Hoffman, Jacqui E.,Le, Phuong T.,Pairish, Mason,Kania, Robert,Farrell, William,Bagrodia, Shubha,Yuan, Jing,Sun, Shaoxian,Zhang, Eric,Xiang, Cathy,Dalvie, Deepak,Rahavendran, Sadayappan V.

supporting information, p. 2787 - 2792 (2013/07/04)

PI3K, AKT and mTOR, key kinases from a frequently dysregulated PI3K signaling pathway, have been extensively pursued to treat a variety of cancers in oncology. Clinical trials of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR, from 4-methylpyridopyrimidinone series, led to the discovery of a metabolite with a terminal carboxylic acid, PF-06465603. This paper discusses structure-based drug design, SAR and antitumor activity of the MPP derivatives with a terminal alcohol, a carboxylic acid or a carboxyl amide.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1013099-51-8