1013314-28-7Relevant articles and documents
The 1,4-benzodiazepine-2,5-dione small molecule template results in melanocortin receptor agonists with nanomolar potencies
Joseph, Christine G.,Wilson, Krista R.,Wood, Michael S.,Sorenson, Nicholas B.,Phan, Dong V.,Xiang, Zhimin,Witek, Rachel M.,Haskell-Luevano, Carrie
, p. 1423 - 1431 (2008/09/21)
The melanocortin system consists of five seven-transmembrane spanning G-protein coupled receptors (MC1-5) that are stimulated by endogenous agonists and antagonized by the only two known endogenous antagonists of GPCRs, agouti and agouti-related protein (