1013403-68-3

Basic information

• Product Name: 2-(2-difluoromethylbenzimidazol-1-yl)-4-{4-[N-(2-dimethylaminoethyl)carbamoyl]phenyl}-6-morpholinopyrimidine
• Synonyms: 2-(2-difluoromethylbenzimidazol-1-yl)-4-{4-[N-(2-dimethylaminoethyl)carbamoyl]phenyl}-6-morpholinopyrimidine
• CAS NO: 1013403-68-3
• Molecular Weight: 521.57
• Mol File: 1013403-68-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-difluoromethylbenzimidazol-1-yl)-4-{4-[N-(2-dimethylaminoethyl)carbamoyl]phenyl}-6-morpholinopyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-difluoromethylbenzimidazol-1-yl)-4-{4-[N-(2-dimethylaminoethyl)carbamoyl]phenyl}-6-morpholinopyrimidine(1013403-68-3)
• EPA Substance Registry System: 2-(2-difluoromethylbenzimidazol-1-yl)-4-{4-[N-(2-dimethylaminoethyl)carbamoyl]phenyl}-6-morpholinopyrimidine(1013403-68-3)

Safety Data

• Hazardous Substances Data: 1013403-68-3(Hazardous Substances Data)

Upstream product

• 1013403-37-6 4-(4-carboxyphenyl)-2-(2-difluoromethylbenzimidazol-1-yl)-6-morpholinopyrimidine 
• 108-00-9 N,N-dimethylethylenediamine 
• 95-54-5 1,2-diamino-benzene 
• 705-09-9 2-(difluoromethyl)-1H-benzo[d]imidazole 
• 1012317-17-7 1-[4-chloro-6-(morpholin-4-yl)pyrimidin-2-yl]-2-(difluoromethyl)-1H-benzimidazole 
• 52127-83-0 4-(2,6-dichloropyrimidin-4-yl)morpholine 

Relevant articles and documents

2-BENZIMIDAZOLYL-6-MORPHOLINO-4-PHENYLPYRIMIDINE DERIVATIVES AS PI3K AND MTOR INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS

The invention concerns pyrimidine derivatives of Formula (I), wherein each of p, R1, R2, q, R3, r, R4, X1 and Q1 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in a method for producing an anti-proliferative effect in a warm blooded animal such as man.