1013422-75-7Relevant academic research and scientific papers
One-pot Mukaiyama–Mannich reaction of aldehydes, amines and silyl enol diazoacetate catalyzed by MgI2 etherate
Mi, Nengju,Meng, Xiangwei,Pan, Haokun,He, Kailun,Zhang, Xingxian
, p. 1176 - 1179 (2019)
Three-component Mukaiyama–Mannich reaction of aldehydes, amines, and silyl enol diazoacetoacetate was efficiently carried out to afford δ-amino substituted-α-diazoacetoacetate derivatives catalyzed by 5 mol% of MgI2 etherate (MgI2?(OEt2)n) under mild and neutral reaction conditions in good to excellent yields.
Ruthenium-catalyzed one-pot carbenoid N-H insertion reactions and diastereoselective synthesis of prolines
Deng, Qing-Hai,Xu, Hai-Wei,Yuen, Angella Wing-Hoi,Xu, Zhen-Jiang,Che, Chi-Ming
supporting information; experimental part, p. 1529 - 1532 (2009/04/07)
Aryl- and aliphatic-substituted 3-hydroxyprolines and various other amino esters are conveniently prepared by [RuCI2(p-cymene)] 2-catalyzed one-pot intramolecular and intermolecular carbenoid N-H insertion reactions, respectively, and the prolines are formed with high diastereoselectivities. The catalytic reactions are tolerant toward air/moisture, and the product yields are insensitive to the organic solvents used.
