One-pot Mukaiyama–Mannich reaction of aldehydes, amines and silyl enol diazoacetate catalyzed by MgI2 etherate

Article abstract of DOI:10.1080/10426507.2019.1633322

Three-component Mukaiyama–Mannich reaction of aldehydes, amines, and silyl enol diazoacetoacetate was efficiently carried out to afford δ-amino substituted-α-diazoacetoacetate derivatives catalyzed by 5 mol% of MgI₂ etherate (MgI₂?(OEt₂)_n) under mild and neutral reaction conditions in good to excellent yields.