10138-59-7

Basic information

• Product Name: 1,2-Cyclohexanedicarboxylic acid diethyl ester
• Synonyms: Cyclohexane-1,2-dicarboxylic acid, diethyl ester;cyclohexane-1,2-dicarboxylicacid,diethylester;Diethyl cyclohexane-1,2-dicarboxylate;Diethyl hexahydrophthalate;Diethylester kyseliny hexahydrftalove;diethylesterkyselinyhexahydrftalove;diethylhexahydrophthalate;Hexahydrophthalic acid diethyl ester
• CAS NO: 10138-59-7
• Molecular Formula: C₁₂H₂₀O₄
• Molecular Weight: 228.28
• Mol File: 10138-59-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 135 °C / 11mmHg
• Flash Point: 137.8°C
• Appearance: /
• Density: 1,05 g/cm3
• Vapor Pressure: 0.00164mmHg at 25°C
• Refractive Index: 1.4500-1.4540
• CAS DataBase Reference: 1,2-Cyclohexanedicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Cyclohexanedicarboxylic acid diethyl ester(10138-59-7)
• EPA Substance Registry System: 1,2-Cyclohexanedicarboxylic acid diethyl ester(10138-59-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RTECS: GU9275000
• Hazardous Substances Data: 10138-59-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 28, p. 262, 1980 DOI: 10.1248/cpb.28.262

InChI:InChI=1/C12H20O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h9-10H,3-8H2,1-2H3

Upstream product

• 610-09-3 (1R,2S)-cyclohexane-1,2-dicarboxylic acid 
• 13043-60-2 diethyl 1,2,3,6-tetrahydrophthalate 
• 1520-50-9 but-2-enedioic acid diethyl ester 
• 84-66-2 Diethyl phthalate 
• 2050-23-9 diethyl suberate 
• 64-17-5 ethanol 
• 2305-32-0 trans-1,2-cyclohexanedicarboxylic acid 

Downstream Products

• 84-66-2 Diethyl phthalate 
• 100250-02-0 1,1,3,3-tetramethyl-octahydro-isobenzofuran 
• 105911-18-0 1,2-bis-(α-hydroxy-isopropyl)-cyclohexane 
• 3971-29-7 1,2-bis(hydroxymethyl)cyclohexane 
• 32003-11-5 cyclohexane-1,2-dicarboxylic acid dihydrazide 
• 2305-32-0 trans-1,2-cyclohexanedicarboxylic acid 

Relevant articles and documents

CATALYTIC SYNTHESIS OF N-ALKYLOCTAHYDROISOINDOLES

Catalytic hydroamination of 1,2-bis(hydroxymethyl)cyclohexane by aliphatic nitriles over a nickel catalyst yielded a series of N-alkyl-substituted octahydroisoindoles.Conditions for their synthesis were selected.The IR, PMR, and mass spectra and the proba

Titanium(III)-Oxo Clusters in a Metal-Organic Framework Support Single-Site Co(II)-Hydride Catalysts for Arene Hydrogenation

Titania (TiO2) is widely used in the chemical industry as an efficacious catalyst support, benefiting from its unique strong metal-support interaction. Many proposals have been made to rationalize this effect at the macroscopic level, yet the underlying molecular mechanism is not understood due to the presence of multiple catalytic species on the TiO2 surface. This challenge can be addressed with metal-organic frameworks (MOFs) featuring well-defined metal oxo/hydroxo clusters for supporting single-site catalysts. Herein we report that the Ti8(μ2-O)8(μ2-OH)4 node of the Ti-BDC MOF (MIL-125) provides a single-site model of the classical TiO2 support to enable CoII-hydride-catalyzed arene hydrogenation. The catalytic activity of the supported CoII-hydride is strongly dependent on the reduction of the Ti-oxo cluster, definitively proving the pivotal role of TiIII in the performance of the supported catalyst. This work thus provides a molecularly precise model of Ti-oxo clusters for understating the strong metal-support interaction of TiO2-supported heterogeneous catalysts.

PROCESS FOR HYDROGENATION OF POLYCARBOXYLIC ACIDS OR DERIVATIVES THEROF

The disclosure provides a process for hydrogenation of polycarboxylic acids or derivatives thereof, including: hydrogenation of polycarboxylic acids or derivatives thereof in the presence of a catalyst, wherein the catalyst includes an active metal and a