1014-78-4 Usage
Uses
Used in Pharmaceutical Research:
6-chloro-N-phenylpyridazin-3-amine is used as a chemical intermediate for the synthesis of pharmaceutical drugs, leveraging its unique structure and potential biological activities to contribute to the development of new therapeutic agents.
Used in Medicinal Chemistry:
As a compound with potential therapeutic effects, 6-chloro-N-phenylpyridazin-3-amine is used in medicinal chemistry to explore its interactions with biological targets, which may lead to the discovery of new drugs with specific indications.
Used in Agrochemical Development:
6-chloro-N-phenylpyridazin-3-amine is utilized as a building block in the synthesis of agrochemicals, where its chemical properties may offer novel solutions for pest control and crop protection.
Used in Chemical Synthesis:
In the broader field of chemical synthesis, 6-chloro-N-phenylpyridazin-3-amine is used as a key component in the creation of a variety of organic compounds, contributing to the advancement of chemical libraries and the discovery of new chemical entities with diverse applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1014-78-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,1 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1014-78:
(6*1)+(5*0)+(4*1)+(3*4)+(2*7)+(1*8)=44
44 % 10 = 4
So 1014-78-4 is a valid CAS Registry Number.
1014-78-4Relevant academic research and scientific papers
TRIAZOLOPYRIDAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE
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Page/Page column 22, (2008/12/06)
The present invention relates to a novel triazolopyridazine derivative or a pharmaceutically acceptable salt thereof, and an Acetyl-CoA Carboxylase2 (ACC2) comprising same as an active ingredient. The triazolopyridazine derivative of the present invention
Imidazopyridazines. VIII. Syntheses and Central Nervous System Activities of Some 6-Benzylamino(and methoxybenzylamino)-3-methoxy-2-phenyl(substituted phenyl or pyridinyl)imidazopyridazines
Barlin, Gordon B.,Davies, Les P.,Ngu, Maria M. L.
, p. 1759 - 1768 (2007/10/02)
Syntheses and IC50 values for the displacement of 3H-diazepam from rat brain plasma membrane are reported for a series of 6-benzylamino(and methoxybenzylamino)-3-methoxy-2-phenyl(substituted phenyl and pyridinyl)imidazopyridazines (and their 6-anilino and 6-phenethylamino analogues).The results are compared with those reported previously (by us) for the 6-chloro, 6-phenoxy, 6-benzylthio, and 6-benzyloxy compounds.In the imidazopyridazine ring system, 6-(o- and m-methoxybenzylamino) groups were found to be beneficial to binding activity; eight compounds have been prepared with IC50 values less than 2 nM (cf. 3H-diazepam with IC50 of 4.2 nM). 2-(p-Aminophenyl)-3-methoxy-6-(m-methoxybenzylamino)imidazopyridazine exhibited the highest activity with IC50 1.0 nM.
