101404-06-2Relevant academic research and scientific papers
Enantioselective synthesis of amaryllidaceae alkaloids (+)-vittatine, (+)-epi-vittatine, and (+)-buphanisine
Wei, Meng-Xue,Wang, Cheng-Tao,Du, Ji-Yuan,Qu, Hu,Yin, Pei-Rong,Bao, Xu,Ma, Xiao-Yan,Zhao, Xian-He,Zhang, Guo-Biao,Fan, Chun-An
, p. 1966 - 1971 (2013)
Cat. on a hot tin roof: Enantioselective catalytic Michael addition of α-cyanoketones to acrylates under bifunctional organocatalysis was used to construct the unique arylic all-carbon quaternary stereocenter, which is synthetically crucial in the chemical synthesis of optically pure cis-aryl hydroindole alkaloids. The protocol offers an asymmetric route to (+)-vittatine, (+)-epi-vittatine, and (+)-buphanisine. Copyright
