101411-53-4Relevant articles and documents
Synthesis, calcium channel antagonist activity, and anticonvulsant activity of 3-ethyl 5-methyl 1,4-dihydro-2-[(2-hydroxyethoxy)methyl]6-methyl- 4-(2,3-dichlorophenyl)-3,5-pyridinedicarboxylate coupled to a 1-methyl-1,4- dihydropyridyl-3-carbonyl chemical
Yiu, Sai-Hay,Knaus, Edward E.
, p. 363 - 367 (1999)
3-Ethyl 5-methyl 1,4-dihydro-2-[(2-hydroxyethoxy)methyl]-6-methyl-4- (2,3-dichlorophenyl)-3,5-pyridinedicarboxylate (13), a bioisostere of amlodipine, was prepared by the reaction of ethyl 4-(2- hydroxyethoxy)acetoacetate (11) with methyl 2-(2,3- dichloro
Antihypertensive 2-hydroxyalkoxyalkyl dihydropyridines
-
, (2008/06/13)
Compounds of the formula: STR1 where R is an optionally substituted aryl or heteroaryl group; R1 and R2 are each independently C1 -C4 alkyl or 2-methoxyethyl; and Y is --(CH2)n -- where n i