1014394-72-9

Basic information

• Product Name: (E)-3-(4-methoxyphenyl)allyl pivalate
• Synonyms: (E)-3-(4-methoxyphenyl)allyl pivalate
• CAS NO: 1014394-72-9
• Molecular Weight: 248.322
• Mol File: 1014394-72-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-3-(4-methoxyphenyl)allyl pivalate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-methoxyphenyl)allyl pivalate(1014394-72-9)
• EPA Substance Registry System: (E)-3-(4-methoxyphenyl)allyl pivalate(1014394-72-9)

Safety Data

• Hazardous Substances Data: 1014394-72-9(Hazardous Substances Data)

Upstream product

• 53484-50-7 (E)-p-methoxy-cinnamyl alcohol 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 18657-10-8 (E)-1-methoxy-4-(pent-1-en-1-yl)benzene 
• 113260-51-8 1-methoxy-4-(pent-1-en-3-yl)benzene 
• 1289638-89-6 (E)-1,2,3,4,5-pentafluoro-6-[3-(4-methoxyphenyl)allyl]benzene 
• 1314581-34-4 (E)-1,2,4,5-tetrafluoro-3-methoxy-6-(3-(4-methoxyphenyl)allyl)benzene 
• 1314581-36-6 (E)-1,2,4,5-tetrafluoro-3-(3-(4-methoxyphenyl)allyl)-6-(trifluoromethyl)benzene 
• 1314581-31-1 (E)-1,2,4,5-tetrafluoro-3-(3-(4-methoxyphenyl)allyl)benzene 
• 1314581-33-3 (E)-1,2,3,5-tetrafluoro-4-(3-(4-methoxyphenyl)allyl)benzene 
• 1314581-38-8 (E)-1,3,5-trifluoro-2-(3-(4-methoxyphenyl)allyl)benzene 

Relevant articles and documents

Palladium-Catalyzed Allylation of Polyfluoroarenes with Allylic Pivalates

An efficient 1,5-cyclooctadiene-PdCl 2 /dicyclohexyl(2′,4′,6′-triisopropylbiphenyl-2-yl)phosphine (XPhos) catalytic system was developed for C-H allylation of polyfluoroarenes with allylic pivalates. The reactions showed excellent functional-group tolerance, good yields, and high regioselectivities. Mechanistic investigations supported a (π-allyl)palladium complex pathway through a directed oxidative addition of the allylic pivalate to palladium, followed by sequential nucleophilic attack by the polyfluorobenzene and reductive elimination. In a gram-scale reaction, a palladium loading of 0.5 mol% was enough to afford the required product in good yield.