10147-69-0Relevant articles and documents
Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents
Elkamhawy, Ahmed,Kim, Nam youn,Hassan, Ahmed H.E.,Park, Jung-eun,Paik, Sora,Yang, Jeong-Eun,Oh, Kwang-Seok,Lee, Byung Ho,Lee, Mi Young,Shin, Kye Jung,Pae, Ae Nim,Lee, Kyung-Tae,Roh, Eun Joo
, (2020)
Selective kinase inhibitors development is a cumbersome task because of ATP binding sites similarities across kinases. On contrast, irreversible allosteric covalent inhibition offers opportunity to develop novel selective kinase inhibitors. Previously, we
A highly selective and sensitive fluorescent chemosensor for Fe 3+ in physiological aqueous solution
Hua, Jun,Wang, Yan-Guang
, p. 98 - 99 (2005)
A novel fluorescent chemosensor in which two aza-18-crown-6 moieties are linked to a coumarin fluorophore has been synthesized for sensing Fe 3+. The selective fluorescence enhancement was observed upon binding Fe3+ at physiological
Antidiabetic compounds
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Page/Page column 13-14, (2020/06/16)
Compounds for the treatment of hyperglycemia and/or diabetes are provided. The compounds, which inhibit the enzyme dipeptidyl peptidase (DPP-4), are based on the structure where X may be present or absent an may be OH, Ar is an aryl group; and n ranges from 0 to 5.