1015474-85-7

Basic information

• Product Name: 2-amino-6-chloro-N-(2,6-dioxopiperidin-3-yl)benzamide
• Synonyms: 2-amino-6-chloro-N-(2,6-dioxopiperidin-3-yl)benzamide
• CAS NO: 1015474-85-7
• Molecular Weight: 281.699
• Mol File: 1015474-85-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-amino-6-chloro-N-(2,6-dioxopiperidin-3-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-6-chloro-N-(2,6-dioxopiperidin-3-yl)benzamide(1015474-85-7)
• EPA Substance Registry System: 2-amino-6-chloro-N-(2,6-dioxopiperidin-3-yl)benzamide(1015474-85-7)

Safety Data

• Hazardous Substances Data: 1015474-85-7(Hazardous Substances Data)

Upstream product

• 2148-56-3 2-chloro-6-aminobenzoic acid 
• 20829-96-3 5-chloro-1H-benzo[d][1,3]oxazine-2,4-dione 
• 2353-44-8 (+/-)-α-aminoglutarimide 
• 24666-56-6 rac-α-aminoglutarimide hydrochloride 

Relevant articles and documents

NOVEL PIPERIDINE-2,6-DIONE DERIVATIVE AND USE THEREOF

The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.

5-SUBSTITUTED QUINAZOLINONE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME

Provided are 5-substituted quinazolinone compounds, and pharmaceutically acceptable salts, solvates, clathrates, stereoisomers, and prodrugs thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.