1015479-61-4

Basic information

• Product Name: 3-(3-chlorophenyl)-N-cyclohexyl-5-(4-methoxyphenyl)-2-oxo-2,3-dihydrooxazole-4-carboxamide
• Synonyms: 3-(3-chlorophenyl)-N-cyclohexyl-5-(4-methoxyphenyl)-2-oxo-2,3-dihydrooxazole-4-carboxamide
• CAS NO: 1015479-61-4
• Molecular Weight: 426.9
• Mol File: 1015479-61-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-chlorophenyl)-N-cyclohexyl-5-(4-methoxyphenyl)-2-oxo-2,3-dihydrooxazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-chlorophenyl)-N-cyclohexyl-5-(4-methoxyphenyl)-2-oxo-2,3-dihydrooxazole-4-carboxamide(1015479-61-4)
• EPA Substance Registry System: 3-(3-chlorophenyl)-N-cyclohexyl-5-(4-methoxyphenyl)-2-oxo-2,3-dihydrooxazole-4-carboxamide(1015479-61-4)

Safety Data

• Hazardous Substances Data: 1015479-61-4(Hazardous Substances Data)

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 108-42-9 3-chloro-aniline 
• 1076-95-5 p-methoxyphenylglyoxal 
• 76-03-9 trichloroacetic acid 

Relevant articles and documents

A one-pot, ugi four-component synthesis of 2(3H)-oxazolone 4-carboxamides

Ugi reaction between arylglyoxals, anilines, cyclohexyl isocyanide and trichloroacetic acid in dichloromethane, in the presence of molecular sieves, afforded 2(3H)-oxazolone 4-carboxamides in good yields by a one-pot process that involved an in situ spontaneous cyclization of the Ugi product through an intermediate ketone enolate and the chloroacetate carbonyl group. The synthesis is based on the ability of the trichloroacetyl group to function as a masked carbonic acid surrogate. Georg Thieme Verlag Stuttgart.