101620-01-3 Usage
The chemical is a type of carboxylic acid
It contains a carboxyl group (-COOH) which gives it acidic properties.
It contains a conjugated diene structure
It has two carbon-carbon double bonds that are separated by a single bond, which allows for the delocalization of electrons and the formation of a conjugated system.
It is also known as Eudistomins
This is the common name for this chemical, which is derived from the marine organism it is isolated from.
It is isolated from the marine organism Eudistoma olivaceum
This is the source of the chemical, which is a type of sea sponge.
It has various biological activities
The chemical has been found to have anti-inflammatory and anticancer properties.
It has a unique chemical structure
The chemical has a complex and distinctive structure, which includes a carboxylic acid group, a conjugated diene system, and multiple methoxy and ethoxy groups attached to a phenyl ring.
It has promising pharmaceutical applications
Due to its unique structure and biological activities, the chemical is of interest to researchers for its potential use in the development of new drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 101620-01-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,6,2 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 101620-01:
(8*1)+(7*0)+(6*1)+(5*6)+(4*2)+(3*0)+(2*0)+(1*1)=53
53 % 10 = 3
So 101620-01-3 is a valid CAS Registry Number.
101620-01-3Relevant academic research and scientific papers
(2E,4E)-N-(4-(1H-indol-3-yl)piperidin-1-yl)alkyl-5-(substituted phenyl)-2,4-pentadienamides as antiallergic agents with antihistaminic and anti slow-reacting substance (SRS) activities
Shigenaga,Manabe,Matsuda,Fujii,Matsuo
, p. 3 - 10 (2007/10/02)
As an extension of our study aiming to discover a novel compound with dual activities against histamine and slow-reacting substance (SRS), we synthesized two types of indolylpiperidine derivatives, 3 and 4-20. Testing for in vivo antianaphylactic activity and for in vitro anti-SRS activity revealed that (2E,4E)-5-(3,5-dimethoxy-4-hydroxyphenyl)-N-(2-(4-(1H-indol-3-yl)piper idin-1-yl)ethyl)-2,4-pentadienamide (11) exhibited potent dual activities with ED50 = 0.89 mg/kg and IC50 = 1.43 μM, respectively. However, the plasma concentration of unchanged 11 was very low when administered orally in guinea pigs. This result can be explained by fast formation of a glucuronic acid conjugate.
