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9BETA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID, also known as prostaglandin E2, is a naturally occurring lipid compound that plays a vital role in the body's inflammatory and immune responses. Derived from arachidonic acid, it is produced by various cells, especially in response to injury or infection. Prostaglandin E2 functions as a signaling molecule, influencing processes such as fever, pain perception, and blood vessel dilation. It also impacts the gastrointestinal, reproductive, and respiratory systems. Its diverse biological effects have made prostaglandin E2 a significant target for pharmaceutical research in the development of anti-inflammatory and pain-relieving drugs.

10164-73-5

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10164-73-5 Usage

Uses

Used in Pharmaceutical Research:
9BETA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID is used as a target for pharmaceutical research for the development of anti-inflammatory and pain-relieving drugs due to its crucial role in inflammation and immune response.
Used in Inflammation and Immune Response Regulation:
9BETA,11ALPHA,15S-TRIHDROXY-PROST-13E-EN-1-OIC ACID is used as a signaling molecule in the regulation of inflammation and immune response, modulating processes such as fever, pain perception, and blood vessel dilation.
Used in Gastrointestinal System Regulation:
9BETA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID is used as a regulatory molecule in the gastrointestinal system, influencing its functioning and maintaining homeostasis.
Used in Reproductive System Regulation:
9BETA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID is used as a regulatory molecule in the reproductive system, affecting processes such as fertility and pregnancy.
Used in Respiratory System Regulation:
9BETA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID is used as a regulatory molecule in the respiratory system, influencing its functioning and maintaining respiratory health.

Check Digit Verification of cas no

The CAS Registry Mumber 10164-73-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,6 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 10164-73:
(7*1)+(6*0)+(5*1)+(4*6)+(3*4)+(2*7)+(1*3)=65
65 % 10 = 5
So 10164-73-5 is a valid CAS Registry Number.
InChI:InChI=1/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18+,19+/m0/s1

10164-73-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-[(1R,2R,3R,5R)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]heptanoic acid

1.2 Other means of identification

Product number -
Other names PGF1beta

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10164-73-5 SDS

10164-73-5Downstream Products

10164-73-5Relevant academic research and scientific papers

Regio- and Stereoselectivity of the Reaction between Cyanocuprates and Cyclopentene Epoxides. Application to the Total Synthesis of Prostaglandins

Marino, Joseph P.,Pradilla, Roberto F. de la,Laborde, Edgardo

, p. 4898 - 4913 (2007/10/02)

A systematic study of the reaction between cyclopentene epoxides and alkyl-, alkenyl-, and arylcyanocuprates is described.Alkylcyanocuprates react with complete regio- and stereoselectivity to provide trans-4-alkylcyclopent-2-enols in excellent yields.Vin

Stereocontrolled Synthesis of Prostaglandins from Cyclopentadiene Monoepoxide

Marino, Joseph P.,Pradilla, Roberto Fernandez de la,Laborde, Edgardo

, p. 5279 - 5280 (2007/10/02)

Two complementary syntheses of prostaglandins from the same key intermediate 3, available in four steps from cyclopentadiene monoepoxide, are described.In one approach, a saturated α-chain is introduced via a 1,4-addition of an appropriately functionalized cyanocuprate reagent onto silyl enol ether 3.The resulting prostanoid compound was converted into the bronchodilator 1-decarboxy-1-hydroxymethyl PGE1, PGE1, and PGF1α.The second approach involves the transformation of silyl enol ether 3 into the known prostanoid precursor 11 via selective addition of carbethoxycarbene and subsequent fluoride-induced ring opening of the resulting (silyloxy)cyclopropane carboxylate ester.

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