1016544-88-9Relevant articles and documents
Synthesis and biological evaluation of boronic acid-containing phenstatin analogues
Nakamura, Hiroyuki,Kuroda, Hirokazu,Minegishi, Hidemitsu
experimental part, p. 79 - 87 (2012/09/21)
A series of boronic acid-containing benzophenones was synthesized by introducing a boronic acid as an acceptor-type functional group into the aromatic ring B of the phenstatin skeleton. Among the compounds synthesized, 4c in which a hydroxyl group on the
BENZOPHENONE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE
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Page/Page column 112, (2008/06/13)
Disclosed herein are novel benzophenone derivatives represented by formula I, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof, a pharmacological composition containing the same, and a use of the composition as therapeutic drugs. The benzophenone derivatives have an inhibition activity of microtubule formation and can be used to treat a normal proliferative state of a malignant tumor by killing the actively proliferating cells.