1016669-00-3Relevant articles and documents
Trialkyl Methanetricarboxylate as Dialkyl Malonate Surrogate in Copper-Catalyzed Enantioselective Propargylic Substitution
Huang, Guanxin,Cheng, Cang,Ge, Luo,Guo, Beibei,Zhao, Long,Wu, Xiaoyu
, p. 4894 - 4897 (2015)
The first copper-catalyzed enantioselective propargylation of trialkyl methantricarboxylate with propargylic alcohol derivatives was developed. The tricarboxylate unit in the obtained adducts could be easily transformed into a malonate moiety by treating with in situ generated NaOEt in excellent yield without racemization.
Gold catalysis: Highly functionalized cyclopentadienes prepared by intermolecular cyclization of ynamides and propargylic carboxylates
Rettenmeier, Eva,Schuster, Andreas M.,Rudolph, Matthias,Rominger, Frank,Gade, Christoph A.,Hashmi, A. Stephen K.
, p. 5880 - 5884 (2013)
When an ynamide meets a gold carbenoid: Highly electrophilic gold carbenoids available from propargylic esters by means of 1,2-acyloxy migration open up new reaction pathways for ynamide gold chemistry. In this way highly functionalized cyclopentadiene derivatives become accessible (see scheme; EWG=electron-withdrawing group). Copyright