1016681-36-9

Basic information

• Product Name: 2-chloro-6-(cyclohexyloxy)pyrazine
• Synonyms: 2-chloro-6-(cyclohexyloxy)pyrazine
• CAS NO: 1016681-36-9
• Molecular Weight: 212.679
• Mol File: 1016681-36-9.mol

Chemical Properties

• CAS DataBase Reference: 2-chloro-6-(cyclohexyloxy)pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-(cyclohexyloxy)pyrazine(1016681-36-9)
• EPA Substance Registry System: 2-chloro-6-(cyclohexyloxy)pyrazine(1016681-36-9)

Safety Data

• Hazardous Substances Data: 1016681-36-9(Hazardous Substances Data)

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 108-93-0 cyclohexanol 

Relevant articles and documents

Synthesis and evaluation of 5-(3-(Pyrazin-2-yl)benzylidene)thiazolidine-2,4-dione derivatives as pan-pim kinases inhibitors

Pim kinases play a key role in the regulation of signaling pathways including proliferation, migration, and metabolism and are a potential target for cancer therapy. A series of 5-benzylidenethiazolidine-2,4-diones were synthesized as pim kinase inhibitor

THERAPEUTIC COMPOUNDS

The present invention relates to pyrazine substituted pyrrolopyridines which are inhibitors of JAK kinases (JAKl, JAK2, JAK3 and/or TYK2) and/or PDKl and are thus useful for the treatment of myeloproliferative disorders or cancer.