1016804-06-0

Basic information

• Product Name: 7-broMo-3,4-dihydro-2H-chroMen-4-aMine
• Synonyms: 7-broMo-3,4-dihydro-2H-chroMen-4-aMine;7-BROMOCHROMAN-4-AMINE HCL;7-BROMOCHROMAN-4-AMINE
• CAS NO: 1016804-06-0
• Molecular Formula: C9H10BrNO
• Molecular Weight: 228.0858
• Mol File: 1016804-06-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-broMo-3,4-dihydro-2H-chroMen-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-broMo-3,4-dihydro-2H-chroMen-4-aMine(1016804-06-0)
• EPA Substance Registry System: 7-broMo-3,4-dihydro-2H-chroMen-4-aMine(1016804-06-0)

Safety Data

• Hazardous Substances Data: 1016804-06-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
7-broMo-3,4-dihydro-2H-chroMen-4-aMine is used as a potential drug candidate for the development of new medications. Its pharmacological properties and unique chemical structure make it a promising candidate for the treatment of various diseases and conditions.
Used in Research Applications:
In the field of research, 7-broMo-3,4-dihydro-2H-chroMen-4-aMine serves as a tool compound for studying biological pathways and understanding the mechanisms of action of chromen-4-amine derivatives. Its unique bromine substituent allows researchers to explore its reactivity and properties in different chemical and biological contexts.
Used in Chemical Synthesis:
The bromine substituent in 7-broMo-3,4-dihydro-2H-chroMen-4-aMine provides unique reactivity, making it a valuable intermediate in the synthesis of other chemical compounds. It can be used in various chemical reactions to produce novel molecules with potential applications in various industries.
Used in Drug Delivery Systems:
7-broMo-3,4-dihydro-2H-chroMen-4-aMine can be incorporated into drug delivery systems to improve the bioavailability and therapeutic outcomes of medications. Its unique properties may allow for targeted delivery to specific cells or tissues, enhancing the efficacy of treatments.
Used in Chemical and Biological Applications:
The unique reactivity and properties of 7-broMo-3,4-dihydro-2H-chroMen-4-aMine make it a valuable compound for various chemical and biological applications. Its bromine substituent can be exploited for different purposes, such as in the development of new materials, sensors, or diagnostic tools.

Upstream product

• 27407-19-8 7-bromochroman-4-one oxime 
• 1392072-40-0 (rac)-4-azido-7-bromochroman 
• 18385-82-5 7-bromochroman-4-ol 
• 18442-22-3 7-Bromo-2,3-dihydro-4H-chromen-4-one 

Relevant articles and documents

NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST GLUCOSYLCERAMIDE SYNTHASE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PROCESSES FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME

The present invention provides a novel compound having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof, a process for the preparation thereof, a pharmaceutical composition comprising the same and a use thereof. The compound having a chromane, isochromane, thiochromane, or tetrahydroquinoline moiety or pharmaceutically acceptable salt thereof has an inhibitory activity against glucosylceramide synthase (GCS), and therefore can be usefully applied for preventing or treating various diseases associated with GCS, such as Gaucher disease, Fabry disease, Tay-Sachs disease, Parkinson's disease, etc.

DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS

Provided are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein A, Z, B, R1, R2, R3, G1, G2, and G3 are as defined herein. Also provided is a pharmaceutically acceptable composition comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof Also provided are methods of using a compound of Formula (I), or a pharmaceutically acceptable salt, thereof for use in methods of treatment heart diseases through cardiac sarcomere inhibtion.

SUBSTITUTED CHROMANES AND METHOD OF USE

The invention provides for compounds of formula (I), wherein R1, X, Y, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, m, and R" have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by CFTR, including cystic fibrosis, Sj?gren's syndrome, pancreatic insufficiency, chronic obstructive lung disease, and chronic obstructive airway disease. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (I).

BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY

The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.

NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES

The invention provides novel compounds having the general Formula (I), wherein R1, R2, R3, R4 R5, R6, R7, R8 R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.