1016805-07-4

Upstream product

• 149366-79-0 3-(RS)-(N-tert-butoxycarbonylaminomethyl)pyrrolidine 
• 1610505-79-7 [1-(4-trifluoromethylphenyl)pyrrolidin-3-ylmethyl]carbamic acid tert-butyl ester 
• 402-43-7 p-trifluoromethylphenyl bromide 

Downstream Products

• 1610505-69-5 2-[ethyl-(4-fluorobenzenesulfonyl)amino]-N-[1-(4-trifluoromethylphenyl)pyrrolidin-3-ylmethyl]acetamide 
• 1610505-70-8 2-(4-fluoro-N-isopropylphenylsulfonamido)-N-((1-(4-(trifluoromethyl)phenyl)pyrrolidin-3-yl)methyl)acetamide 
• 1610505-80-0 [4-(4-trifluoromethylphenyl)morpholin-2-ylmethyl]carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

NOVEL ACETAMIDE DERIVATIVES AS TRP CHANNEL ANTAGONISTS

The invention is concerned with a compound of formula (I) and pharmaceutically acceptable salts thereof wherein R1 to R3, X and Y are as defined as in the description and in the claims. The compound of formula (I) can be used as a medicament for therapy and/or prophylaxis in a mammal of an inflammatory disease or disorder, and in particular to Transient Receptor Potential (TRP) channel antagonists.