101685-29-4Relevant academic research and scientific papers
Rational design of novel near-infrared fluorescent DCM derivatives and their application in bioimaging
Wang, Xiaohang,Guo, Zhiqian,Zhu, Shiqin,Liu, Yajing,Shi, Ping,Tian, He,Zhu, Wei-Hong
, p. 4683 - 4689 (2016)
The development of innovative strategies for high-performance near-infrared (NIR) fluorescent materials is in urgent demand for bioimaging. By replacing the stronger electron-withdrawing groups or extending the π-conjugated system, novel NIR fluorescent materials of DCM analogues have been developed, along with several striking characteristics: bright NIR fluorescence over 700 nm, large Stokes shift and good photo-stability. It is demonstrated that introducing a stronger electron-withdrawing unit to the acceptor moiety of DCM analogues is a favourably efficient strategy to tune and prolong the emission wavelength into the NIR region with a large Stokes shift. In comparison with the commercial NIR dye ICG, S-DCM-N and S-DCM-P display excellent photostability and low photobleaching. The large Stokes Shift and NIR fluorescence channel of S-DCM-N and S-DCM-P are very favourable for fluorescence labelling with a high signal-to-noise ratio in living species.
New data about the reaction of benzyolacetonitrile with malononitrile and its self-condensation
Abdelrazek, Fathy M.,Michael, Farid A.
, p. 7 - 10 (2007/10/03)
The reactions of benzoylacetonitrile with malononitrile in refluxing pyridine and its self condensation under fusion conditions in the presence of ammonium acetate and in refluxing pyridine were reinvestigated. New data were found and plausible mechanisms to account for the formation of the products are suggested.
Synthesis of some new heterocycles derived from arylmethylenemalononitriles
El-Sayed,Khodairy
, p. 3331 - 3343 (2007/10/03)
Arylmethylenemalononitriles 1 were treated with halo compounds under phase transfer catalysis (PTC) conditions to yield α-polyfunctional arylmethylene-malononitrile derivatives 2-4. The treatment of compounds 2-4 with hydrazine hydrate gave pyridinones 5,
α,β-Unsaturated Nitriles in Heterocyclic Synthesis: Synthesis of Several Arylpyridine and Arylpyridazine Derivatives
Elgemeie, Galal Hamza,Elfahham, Hassan Attia,Ibrahiem, Yusria Rizk,Elnagdi, Mohamed Hilmy
, p. 535 - 540 (2007/10/02)
Several new azabiaryls and diazabiaryls were synthesized utilizing readily obtainable α,β-unsaturated nitriles.
ACTIVATED NITRILES IN HETEROCYCLIC SYNTHESIS : NOVEL SYNTHESIS OF PYRIDAZINES, PYRIDINES, PYRAZOLES AND POLYFUNCTIONALLY SUBSTITUTED BENZENE DERIVATIVES
Elgemeie, Galal Eldin Hamza,Elfahham, Hassan Attia,Elgamal, Sherif,Elnagdi, Mohamed Hilmy
, p. 1999 - 2003 (2007/10/02)
Knoevenagel condensation of benzoylacetonitrile with malononitrile afforded the corresponding ylidene derivative which could be converted into pyridazine derivative on coupling with benzenediazonium chloride and cyclization.Similarly benzoylacetonitrile u
