101689-08-1

Basic information

• Product Name: (R)-N-((R)-1,2-Dimethyl-propyl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide
• CAS NO: 101689-08-1
• Molecular Weight: 303.325
• Mol File: 101689-08-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-N-((R)-1,2-Dimethyl-propyl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-((R)-1,2-Dimethyl-propyl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide(101689-08-1)
• EPA Substance Registry System: (R)-N-((R)-1,2-Dimethyl-propyl)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionamide(101689-08-1)

Safety Data

• Hazardous Substances Data: 101689-08-1(Hazardous Substances Data)

Upstream product

• 64312-89-6 Mosher's acid chloride 
• 758-27-0 (R)-1,2-dimethylpropylamine hydrochloride 
• 2026-48-4 (S)-valinol 
• 72-18-4 L-valine 
• 4070-48-8 L-Valine methyl ester 
• 55424-48-1 (S)-2-(4-methylphenylsulfonylamino)-1-(4-methylsulfonyloxy)-3-methylbutane 
• 51859-00-8 (R)-N-1-(i-propyl)ethyltosylamide 
• 598-74-3 (2R)-3-methyl-2-butylamine 
• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 563-80-4 3-methyl-butan-2-one 
• 25102-89-0 (2R)-3-methyl-N-((R)-1-phenylethyl)butan-2-amine 

Relevant articles and documents

SYNTHESIS OF THE RACEMIC FORM OF (Z)-1,17-DIAMINOOCTADEC-9-ENE, AN ALIPHATIC DIAMINE FROM COCCINELLIDAE. DETERMINATION OF THE ABSOLUTE CONFIGURATION OF THE (+)-NATURALLY-OCCURRING ANTIPODE

The total synthesis of the title compound (1) has been achieved.Also reported is the use of lanthanide induced shifts in 1H NMR spectroscopy to assign the absolute configuration of the α-carbon atom in chiral primary α-methylalkylamines.Application of this empirical method to natural (+)-1 shows that it has the R-configuration at C-17.