1016896-38-0Relevant articles and documents
Highly enantioselective dynamic kinetic resolution of 1,2-diarylethanols by a lipase-ruthenium couple
Kim, Mahn-Joo,Choi, Yoon Kyung,Kim, Sol,Kim, Daeho,Han, Kiwon,Ko, Soo-Byung,Park, Jaiwook
, p. 1295 - 1298 (2008)
A practical procedure has been developed for the dynamic kinetic resolution of 1,2-diarylethanols. This procedure employs a highly enantioselective lipase from Pseudomonas stutzeri (trade name, lipase TL) as the resolution catalyst and a ruthenium complex as the racemization catalyst. Sixteen 1,2-diarylethanols have been efficiently resolved to provide their acetyl derivatives with good yields (95-97%) and high enantiomeric excesses (96-99%).