101692-75-5Relevant academic research and scientific papers
Chiral Bicyclic Lactams for Asymmetric Synthesis of Quaternary Carbons. The Total Synthesis of (-)-α-Cuparenone
Meyers, A. I.,Lefker, Bruce A.
, p. 1541 - 1544 (2007/10/02)
An asymmetric synthesis of the title compounds has been achieved in >98percent ee using chiral bicyclic lactams 14 derived from (S)-valinol and γ-keto acids.Thus, cyclocondensation of racemic 2-p-tolyl-4-oxopentanoic acid with (S)-valinol gave a 1:1 mixtu
