1017-07-8Relevant academic research and scientific papers
Synthesis and properties of 3-alkyl(aryl)-5-chloromethylisoxazoles
Gadzhily,Aliev
, p. 415 - 418 (2007/10/03)
3-Chloro-2-isothiocyanato-1-propenyl alkyl(aryl) ketones react with hydroxylamine hydrochloride to give 3-alkyl(aryl)-5-chloromethylisoxazole. Treatment of the latter with dimethylamine and ammonium thiocyanate leads to formation of previously unknown 3-alkyl(aryl)-5-dimethylamino(or isothiocyanato)-methylisoxazoles.
Regioisomeric 5(3)-aminomethyl-3(5)-phenylisoxazoles: Synthesis, spectroscopic discrimination, and muscarinic activity
Dannhardt,Lambrecht,Laufer,Mutschler,Schweiger
, p. 437 - 443 (2007/10/02)
The regioselective synthesis of isomeric 5(3)-aminomethyl-3(5)-phenyl isoxazoles using different methods is described. Spectroscopic data, especially mass spectrometric fragmentation, were used to identify and characterize the regioisomers. The muscarinic
