10172-35-7 Usage
Description
2-Bromo-4-Methoxy-6-nitroaniline, also known as 2-BroMo-4-Methoxy-6-nitroaniline, is a chemical compound with the molecular formula C7H6BrN3O3. It is a derivative of aniline, featuring both bromine and nitro groups. This yellow solid at room temperature is utilized in various chemical processes and industries, but requires careful handling due to its potential environmental and health hazards.
Uses
Used in Pharmaceutical Synthesis:
2-BroMo-4-Methoxy-6-nitroaniline is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2-BroMo-4-Methoxy-6-nitroaniline is used as a precursor in the production of various agrochemicals, playing a role in the creation of substances that protect crops and enhance agricultural productivity.
Used in Dyes and Pigments Manufacturing:
2-BroMo-4-Methoxy-6-nitroaniline is utilized as a key component in the manufacturing of dyes and pigments, where its chemical properties contribute to the color and stability of these products.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 2-BroMo-4-Methoxy-6-nitroaniline is employed for its reactivity and structural features that facilitate the formation of a range of organic compounds.
Used in Chemical Manufacturing:
In the broader chemical manufacturing sector, 2-BroMo-4-Methoxy-6-nitroaniline serves as a building block for the production of other chemicals, highlighting its versatility in the chemical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 10172-35-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,7 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10172-35:
(7*1)+(6*0)+(5*1)+(4*7)+(3*2)+(2*3)+(1*5)=57
57 % 10 = 7
So 10172-35-7 is a valid CAS Registry Number.
10172-35-7Relevant articles and documents
SUBSTITUTED QUINAZOLINE COMPOUNDS AND THEIR USE AS INHIBITORS OF G12C MUTANT KRAS, HRAS AND/OR NRAS PROTEINS
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Page/Page column 105, (2017/02/09)
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein R, R1, R2a, R2b, R2c, A, B, L1 and E are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided.
Solid state nuclear bromination with N-bromosuccinimide. Part 1. Experimental and theoretical studies on some substituted aniline, phenol and nitro aromatic compounds
Sarma, Jagarlapudi A.R.P.,Nagaraju, Akula
, p. 1113 - 1118 (2007/10/03)
Solid state bromination of a number of substituted phenol, aniline and nitro aromatic compounds with N-bromosuccinimide yields exclusively the nuclear brominated products. Reactivity in the solid state depends on the reaction time, temperature and nature of the substituent on the substrate. The reaction apparently proceeds by an electrophilic aromatic substitution pathway. Molecular orbital and reaction free energy calculations also support such a view. Thermal analysis and video microscopic observation reveal the nature of the solid state reaction. Crystallinity is required for the reactivity and product selectivity. Product yield decreases with loss of selectivity when the reaction is carried out in a melt or in solution. Unlike the topochemical solid state reactions wherein molecular packing is more important than the intrinsic reactivity, these reactions demonstrate the importance of both these factors.