10172-75-5Relevant academic research and scientific papers
Synthesis of biscoumarin and dihydropyran derivatives as two novel classes of potential anti-bacterial derivatives
Li, Jing,Xue, Xiao-yan,Li, Xia,Hou, Zheng,Yang, Xiao-hui,Qu, Di,Zhou, Ying,Zhang, Zi-dan,Luo, Xiao-xing,Li, Jiang-tao,Li, Ming-kai
, p. 1349 - 1355 (2016)
A series of bisoumarin (1–4) and dihydropyran (5–8) derivatives were successfully synthesized as new antibacterial agents. The molecular structures of three representative compounds 1, 5 and 7 were confirmed by single crystal X-ray diffraction study. Amon
Aldehyde condensation products of 4-hydroxycoumarin and Schiff bases
Manolov, Ilia I.
, p. 3041 - 3042 (1998)
4-Hydroxycoumarin and Schiff bases condense in glacial acetic acid at reflux. Benzylidenephenyliminochroman or 3,3'-(p-substituted- arylmethylidene)-bis-4-hydroxycoumarin are the final products.
Impact of solvents on energy gap, photophysical, photometric properties for a new class of 4-HCM coumarin derivative: Nonlinear optical studies and optoelectronic applications
Pramod,Renuka,Nadaf,Rajaramakrishna
, (2019)
Now a day the derivatives of biscoumarins are receiving overwhelming importance due to their application in designing organic semiconductor materials for display application. Therefore, a new photostable, light emitting and highly efficient synthesized ma
Synthesis of unexpected novel bis-coumarin derivatives via three component reactions of 4-hydroxycoumarin, aldehydes and cyclic secondary amines. Conformation in the solid state and pharmacological evaluation
El-Samahy, Fatma A.,Abd El Salam, Hayam A.,El-Sayed, Naglaa F.,Shalaby, Elsayed M.,Dondeti, Mahmoud F.
, p. 705 - 716 (2017)
A series of unexpected bis-coumarins have been synthesized by multicomponent reactions of 4-hydroxycoumarin, aldehydes, and cyclic secondary amines in ethanol at room temperature. The chemical structures of new compounds were identified by 1H, 13C NMR, and mass spectrometry. Furthermore, the molecular structure of the solid-state adduct of 3,3′-[(4-methoxyphenyl)-methylene] bis(4-hydroxy-2H-chromen-2-one) with morpholine (1:1) has been confirmed by single-crystal X-ray diffraction. The cytotoxicity of the new coumarin derivatives against MCF7 breast cancer cells was evaluated. A docking study of the new products was carried out to assess the molecular affinity between the tested compound and Topoisomerase IIa.
Synthesis, photophysical properties, chemo-sensing ability and computational studies of biscoumarin derivatives
Harichandran, G.,Nehru, S.,Surya, C. P.
, (2021/09/20)
Synthesis of biscoumarin derivatives using an environment friendly,recyclable polymeric resin as catalyst via one-pot pseudo-three component reaction was simply achieved by using numerous substituted aromatic aldehydes (1 mM) and 4-hydroxycoumarin (2 mM)
Facile and Straightforward Synthesis of Racemic Version of Substituted 3-[3-(2-Hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins: Easy Access to a Series of Biorelevant Warfarin Analogues
Brahmachari, Goutam,Mandal, Mullicka,Karmakar, Indrajit
, p. 451 - 464 (2021/10/19)
The present communication deals with a straightforward, efficient, and green synthesis of a series of racemic version of 3-[3-(2- hydroxyphenyl)-3-oxo-1-arylpropyl]-4-hydroxycoumarins as biologically interesting warfarin analogues upon decarboxylative hyd
Chitosan and functionalized graphene oxide nanocomposite as a novel and highly efficient catalyst for production of bis-coumarins under solvent-free conditions
Atashrouz, Zhale,Rostami, Esmael,Zare, Abdolkarim
, p. 179 - 201 (2021/11/18)
Chitosan and functionalized graphene oxide nanocomposite was used as efficient, sustainable, and recyclable catalyst in the production of bis-coumarins using 4-hydroxycoumarin and aromatic aldehydes under solvent-free conditions. Chitosan was first functi
Developing a highly potent anthelmintic: study of catalytic application of l-proline derived aminothiourea in rapid synthesis of biscoumarins and their in vitro anthelmintic essay
Kharrngi, Balamphrang,Dhar, Errini Decruse,Basumatary, Grace,Das, Dharitri,Deka, Ramesh Ch,Yadav, Arun K,Bez, Ghanashyam
, (2021/02/22)
Abstract: Due to serious side effects of benzimidazoles such as apoptosis and mitotic arrest, development of alternative anthelmintic drugs with comparable efficacy to target the acetylcholine receptors of parasites is considered very important to control
Unveiling the anti-tubercular properties of biscoumarins, through biological evaluation and docking studies
Acharya, Poornima,Ramana,Upadhyay, Manish,Pavale, Ganesh
, p. 57 - 66 (2021/02/27)
Background: Biscoumarin scaffolds are known for their promising pharmacological properties. These compounds have not been studied for their activity against tuberculosis strains. Objective: Unveil the antitubercular properties of biscoumarin scaffolds. Me
A synergetic role of Aegle marmelos fruit ash in the synthesis of biscoumarins and 2-amino-4H-chromenes
Patil, Rupesh C.,Shinde, Sachinkumar K.,Patil, Uttam P.,Birajdar, Appasaheb T.,Patil, Suresh S.
, p. 1675 - 1691 (2021/01/11)
Abstract: A dry rind of Aegle marmelos (bael) fruit ash as a synergetic alternative material to an expensive, toxic and corrosive catalysts for the synthesis of biscoumarins and 2-amino-4H-chromenes at ambient temperature in water is reported. The spectro
