1017238-28-6Relevant articles and documents
Synthesis of potent BCRP inhibitor-Ko143
Li, Yuexian,Hayman, Erik,Plesescu, Mihaela,Prakash, Shimoga R.
, p. 1480 - 1483 (2008)
Two routes for the synthesis of potent BCRP inhibitor-Ko143 are reported. The key intermediate, 6-methoxytryptophan derivative, was synthesized by an improved procedure, ytterbium triflate-promoted coupling between 6-methoxyindole and optically active 1-b
INHIBITOR OF BREAST CANCER RESISTANCE PROTEIN (BCRP)
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Paragraph 00109, (2015/04/28)
Disclosed are compounds that inhibit breast cancer resistance protein (BCRP), of which compound (I-1), ((3S, 6S, 12aS)-6-isobutyl-9-methoxy-3-methyl-2,3,6,7, 12, 12a- hexahydropyrazino[1',2': 1,6]pyrido[3,4-b]indole-1,4-dione) or a pharmaceutically accept