107447-05-2 Usage
Uses
Used in Chemical Synthesis:
(1S,3S)-Methyl 1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate is used as a key intermediate in the synthesis of various complex organic molecules. Its unique structural features, including the iso-butyl and methoxy groups, as well as the carboxylate group, make it a valuable building block for creating a wide array of chemical compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1S,3S)-Methyl 1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate is used as a starting material for the development of new drugs. Its structural elements can be modified to explore potential therapeutic applications, such as the creation of novel analgesics, antidepressants, or anti-inflammatory agents.
Used in Material Science:
(1S,3S)-Methyl 1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate is employed in the field of material science for the development of new materials with unique properties. Its incorporation into polymers or other materials can lead to the creation of substances with enhanced stability, conductivity, or other desirable characteristics.
Used in Analytical Chemistry:
In analytical chemistry, (1S,3S)-Methyl 1-isobutyl-7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate can be used as a reference compound or a standard for the calibration of analytical instruments. Its distinct chemical structure and properties make it suitable for such applications, ensuring accurate measurements and reliable results.
Check Digit Verification of cas no
The CAS Registry Mumber 107447-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,4,4 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 107447-05:
(8*1)+(7*0)+(6*7)+(5*4)+(4*4)+(3*7)+(2*0)+(1*5)=112
112 % 10 = 2
So 107447-05-2 is a valid CAS Registry Number.
107447-05-2Relevant articles and documents
Synthesis of a new inhibitor of breast cancer resistance protein with significantly improved pharmacokinetic profiles
Li, Yuexian,Woo, Jiyeon,Chmielecki, Jessica,Xia, Cindy Q.,Liao, Mingxiang,Chuang, Bei-Ching,Yang, Johnny J.,Guan, Miao Y.,Plesescu, Mihaela,Prakash, Shimoga R.
, p. 551 - 555 (2016/01/09)
The design, synthesis, in vitro inhibitory potency, and pharmacokinetic (PK) profiles of Ko143 analogs are described. Compared to commonly used Ko143, the new breast cancer resistance protein (BCRP) inhibitor (compound A) showed the same potency and a sig
INHIBITOR OF BREAST CANCER RESISTANCE PROTEIN (BCRP)
-
, (2015/04/28)
Disclosed are compounds that inhibit breast cancer resistance protein (BCRP), of which compound (I-1), ((3S, 6S, 12aS)-6-isobutyl-9-methoxy-3-methyl-2,3,6,7, 12, 12a- hexahydropyrazino[1',2': 1,6]pyrido[3,4-b]indole-1,4-dione) or a pharmaceutically accept
Synthesis of potent BCRP inhibitor-Ko143
Li, Yuexian,Hayman, Erik,Plesescu, Mihaela,Prakash, Shimoga R.
, p. 1480 - 1483 (2008/09/18)
Two routes for the synthesis of potent BCRP inhibitor-Ko143 are reported. The key intermediate, 6-methoxytryptophan derivative, was synthesized by an improved procedure, ytterbium triflate-promoted coupling between 6-methoxyindole and optically active 1-b
Synthetic Approaches to Fumitremorgins. III. Synthesis of Optically Active Pentacyclic Ring Systems, and Their Oxidation at Ring C
Nakagawa, Masako,Fukushima, Hiroshi,Kawate, Tomohiko,Hongu, Mitsuya,Une, Teruaki,et al.
, p. 23 - 32 (2007/10/02)
Pictet-Spengler reaction of L-tryptophan methyl ester (9) and 6-methoxy-L-tryptophan methyl ester (40) with isovaleraldehyde (10) in methylene chloride in the presence of trifluoroacetic acid gave the cis-tetrahydro-β-carboline (11, 41) as the major isome
