101724-22-5Relevant articles and documents
An expedient one-pot entry to catecholestrogens and other catechol compounds via IBX-mediated phenolic oxygenation
Pezzella, Alessandro,Lista, Liliana,Napolitano, Alessandra,D'Ischia, Marco
, p. 3541 - 3544 (2005)
A one-pot procedure for the preparation of catecholestrogens in over 90% yield is reported, involving oxygenation of 17β-estradiol or estrone with o-iodoxybenzoic acid (IBX) followed by reduction with methanolic NaBH 4. The procedure, which was extended to the o-hydroxylation of a number of representative phenols in good-to-high yields, expands significantly the scope of phenolic oxidation mediated by IBX.
