1017266-39-5Relevant articles and documents
Practical implications of boron-to-zinc transmetalation for the catalytic asymmetric arylation of aldehydes
Jimeno, Ciril,Sayalero, Sonia,Fjermestad, Torstein,Colet, Gisela,Maseras, Feliu,Pericas, Miquel A.
, p. 1098 - 1101 (2008)
(Chemical Equation Presented) Faster than believed: Transmetalation from aryl boronic acids and triaryl boroxines to diethylzinc takes place within minutes following a two-step, low-energy pathway (see picture), according to density functional calculations and reaction microcalorimetry measurements. The experimental conditions for a practical, atom-economical, and highly enantioselective catalytic arylation of a variety of aldehydes have been developed from these data.