1017293-50-3Relevant academic research and scientific papers
Regioselective aliphatic retro-[1,4]-Brook rearrangements
Mori, Yuji,Futamura, Yutaka,Horisaki, Kazumi
, p. 1091 - 1093 (2008/09/21)
A turn-up for the Brook: The relative ease of silyl migration in the aliphatic retro-Brook rearrangements of α,γ-disilyloxy organolithium compounds (see scheme) has been revealed for the first time to be [1,2] ? [1,4]. The increasing size of the silyloxy group at the γ position relative to that at the α position induces higher [1,4] selectivity. (Chemical Equation Presented).
