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101734-07-0

4-(benzyloxy)-6-methoxy-2-methylquinoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 101734-07-0 Structure

  • Basic information

    1. Product Name: 4-(benzyloxy)-6-methoxy-2-methylquinoline
    2. Synonyms: 4-(benzyloxy)-6-methoxy-2-methylquinoline
    3. CAS NO:101734-07-0
    4. Molecular Formula:
    5. Molecular Weight: 279.338
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 101734-07-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(benzyloxy)-6-methoxy-2-methylquinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(benzyloxy)-6-methoxy-2-methylquinoline(101734-07-0)
    11. EPA Substance Registry System: 4-(benzyloxy)-6-methoxy-2-methylquinoline(101734-07-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 101734-07-0(Hazardous Substances Data)

101734-07-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 101734-07-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,1,7,3 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 101734-07:
(8*1)+(7*0)+(6*1)+(5*7)+(4*3)+(3*4)+(2*0)+(1*7)=80
80 % 10 = 0
So 101734-07-0 is a valid CAS Registry Number.

101734-07-0Downstream Products

101734-07-0Relevant articles and documents

Design, synthesis, and evaluation of new 2-(quinoline-4-yloxy)acetamide-based antituberculosis agents

Abbadi, Bruno Lopes,Basso, Luiz Augusto,Bizarro, Cristiano Valim,Borsoi, Ana Flávia,Macchi, Fernanda Souza,Machado, Diana,Machado, Pablo,Paz, Josiane Delgado,Pissinate, Kenia,Rambo, Raoní S.,Ramos, Alessandro Silva,Sperotto, Nathalia,Viveiros, Miguel

, (2020)

Using a classical molecular simplification approach, a series of 36 quinolines were synthesized and evaluated as in vitro inhibitors of Mycobacterium tuberculosis (M. tuberculosis) growth. Structure–activity relationship (SAR) studies leaded to potent antitubercular agents, with minimum inhibitory concentration (MIC) values as low as 0.3 μM against M. tuberculosis H37Rv reference strain. Furthermore, the lead compounds were active against multidrug-resistant strains, without cross-resistance with some first- and second-line drugs. Testing the molecules against a spontaneous mutant strain containing a single mutation in the qcrB gene (T313A) indicated that the synthesized quinolines targeted the cytochrome bc1 complex. In addition, leading compounds were devoid of apparent toxicity to HepG2 and Vero cells and showed moderate elimination rates in human liver S9 fractions. Finally, the selected structures inhibited M. tuberculosis growth in a macrophage model of tuberculosis infection. Taken together, these data indicate that this class of compounds may furnish candidates for the future development of antituberculosis drugs.

Ultrasound-assisted synthesis of 4-alkoxy- 2-methylquinolines: An efficient method toward antitubercular drug candidates

Basso, Luiz Augusto,Bizarro, Cristiano Valim,Borsoi, Ana Flávia,Machado, Pablo,Paz, Josiane Delgado,Pestana, Víctor Zajaczkowski,Pissinate, Kenia,Rambo, Raoní Scheibler

, (2021)

Tuberculosis (TB) has been described as a global health crisis since the second half of the 1990s. Mycobacterium tuberculosis (Mtb), the etiologic agent of TB in humans, is a very successful pathogen, being the main cause of death in the population among

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