1017442-99-7

Basic information

• Product Name: 2-(4-cyclohexylmethyl-piperazin-1-yl)-ethylamine
• Synonyms: 2-(4-cyclohexylmethyl-piperazin-1-yl)-ethylamine
• CAS NO: 1017442-99-7
• Molecular Weight: 225.377
• Mol File: 1017442-99-7.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-cyclohexylmethyl-piperazin-1-yl)-ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-cyclohexylmethyl-piperazin-1-yl)-ethylamine(1017442-99-7)
• EPA Substance Registry System: 2-(4-cyclohexylmethyl-piperazin-1-yl)-ethylamine(1017442-99-7)

Safety Data

• Hazardous Substances Data: 1017442-99-7(Hazardous Substances Data)

Upstream product

• 57184-23-3 1-cyclohexylmethylpiperazine 

Relevant articles and documents

Identification of N-Benzyl 3,5-Dinitrobenzamides Derived from PBTZ169 as Antitubercular Agents

A series of benzamide scaffolds were designed and synthesized by the thiazinone ring opening of PBTZ169, and N-benzyl 3,5-dinitrobenzamides were finally identified as anti-TB agents in this work. 3,5-Dinitrobenzamides D5, 6, 7, and 12 exhibit excellent in vitro activity against the drug susceptive Mycobacterium tuberculosis H37Rv strain (MIC: 0.0625 μg/mL) and two clinically isolated multidrug-resistant strains (MIC 0.016-0.125 μg/mL). Compound D6 displays acceptable safety and better pharmacokinetic profiles than PBTZ169, suggesting its promising potential to be a lead compound for future antitubercular drug discovery.